General description

Native holotransferrin from human plasma. Transferrin is a serum protein involved in iron binding and transport.

Native holotransferrin from human plasma. Transferrin is a major iron binding protein and is found in human plasma or serum at concentrations of 3 mg/ml. Its concentration correlates with the total iron binding capacity of serum and its level is regulated by the availability of iron. It has bacteriostatic and fungistatic activity and is essential for iron utilization by the hemin-synthesizing reticulocytes. Stored in bone marrow as Tf-bound iron.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

100, 500 mg in Plastic ampoule

Physical form

Lyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or add NaN₃ and refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C.

Warning

Toxicity: Standard Handling (A)